Cambodia has low malaria risk overall, with no risk in Phnom Penh and very low risk around Angkor Wat, Siem Reap and Lake Tonle Sap. Malaria tablets are not automatically advised for every itinerary, although they may be considered for higher-risk travellers or routes into low-risk areas, especially where medical access would be limited. The western provinces bordering Thailand need careful assessment because resistance patterns affect antimalarial choices. Dengue risk is present in Cambodia, and the mosquitoes that spread it often bite during the day, including in towns. Chikungunya and Zika are also reported risks. There is no simple tablet that prevents these infections, so repellent, covered skin and choosing accommodation with screens or air conditioning are still practical measures. Hepatitis A is commonly recommended for previously unvaccinated travellers because it spreads through contaminated food and water. Typhoid vaccination is also usually discussed, particularly for longer trips, lower-budget travel, rural areas or visits where food hygiene may be harder to control. Tetanus should be up to date. Japanese encephalitis occurs countrywide, with higher seasonal concern generally between May and October. It is more relevant for longer stays, rural exposure, rice field areas, pig farms, uncertain itineraries or repeated travel. Rabies is also a real consideration, especially for children, cyclists, runners and anyone spending time away from prompt medical treatment. Avoid swimming or wading in untreated freshwater, as schistosomiasis is a risk in Cambodia.